Drug Delivery by Controlling a Supramolecular Host-Guest Assembly with a Reversible Photoswitch.

نویسندگان

  • Nuno Basílio
  • Uwe Pischel
چکیده

The reversibly switchable trans-chalcone/flavylium photochromic system was successfully coupled to the complexation equilibrium of a drug-cucurbit[7]uril host-guest assembly. Hence, the phototriggered release of memantine under illumination at 366 nm was observed. The process can be partially reverted through a thermally activated back reaction.

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عنوان ژورنال:
  • Chemistry

دوره 22 43  شماره 

صفحات  -

تاریخ انتشار 2016